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Medicines Containing Acetaminophen

Acetaminophen is the most common drug ingredient in America. More than 600 medicines contain acetaminophen. These include both prescription medicines and medicines available without a prescription, also called “over-the-counter,” or “OTC” medicines.

To prevent acetaminophen overdose, you need to be able to read labels and recognize when their medicines contain acetaminophen. The active ingredients in OTC medicines are clearly listed on the label, and the word “acetaminophen,” is listed on the front of the package or bottle and in the Active Ingredient section of the Drug Facts label.

Here’s a more detailed list of medicines containing acetaminophen, including prescription medications:

Brand Name Active Ingredient(s) Type of Medication
Tylenol Acetaminophen Over-the-counter (OTC) pain reliever
Excedrin Acetaminophen, aspirin, and caffeine OTC pain reliever
Dayquil Acetaminophen, dextromethorphan, and phenylephrine OTC cold and flu medication
Nyquil Acetaminophen, dextromethorphan, doxylamine, and phenylephrine OTC cold and flu medication
Midol Acetaminophen, caffeine, and pyrilamine OTC menstrual pain reliever
Robitussin Cold + Flu Acetaminophen, dextromethorphan, and phenylephrine OTC cold and flu medication
Theraflu Acetaminophen, pheniramine, and phenylephrine OTC cold and flu medication
Vicks DayQuil Cold & Flu Acetaminophen, dextromethorphan, and phenylephrine OTC cold and flu medication
Vicks NyQuil Cold & Flu Acetaminophen, dextromethorphan, doxylamine, and phenylephrine OTC cold and flu medication
ZzzQuil Acetaminophen, diphenhydramine, and phenylephrine OTC sleep aid and pain reliever
Percocet Acetaminophen and oxycodone Prescription pain reliever
Vicodin Acetaminophen and hydrocodone Prescription pain reliever
Tylenol with Codeine Acetaminophen and codeine Prescription pain reliever
Ultracet Acetaminophen and tramadol Prescription pain reliever
Lortab Acetaminophen and hydrocodone Prescription pain reliever
Norco Acetaminophen and hydrocodone Prescription pain reliever

It’s important to note that taking too much acetaminophen can be dangerous and cause liver damage. Always follow the recommended dosage instructions on the label, and talk to your doctor or pharmacist if you have any questions or concerns about using acetaminophen-containing medications.

On prescription labels, acetaminophen is sometimes listed as “APAP,” “acetam,” or other shorted versions of the word. To know what is in your medicines, read the list of active ingredients on the label each and every time you take a medicine.

You may be surprised to learn just how many medicines contain this acetaminophen:

Common Over-the-Counter Brand Name Medicines Containing Acetaminophen

  • Actifed®
  • Alka-Seltzer Plus LiquidGels®
  • Anacin®
  • Benadryl®
  • Cepacol®
  • Contac®
  • Coricidin®
  • Dayquil®
  • Dimetapp®
  • Dristan®
  • Excedrin®
  • Feverall®
  • Formula 44®
  • Goody’s®
  • Powders Liquiprin®
  • Midol®
  • Nyquil®
  • Panadol®
  • Robitussin®
  • Saint Joseph®
  • Aspirin-Free Singlet®
  • Sinutab®
  • Sudafed®
  • Theraflu®
  • Triaminic®
  • TYLENOL® Brand Products
  • Vanquish®
  • Vicks®
  • Zicam®
  • *And store brands

Common Prescription Medicines Containing Acetaminophen

  • Endocet®
  • Fioricet®
  • Hycotab
  • Hydrocet®
  • Hydrocodone Bitartrate
  • Lortab®
  • Percocet®
  • Phenaphen®
  • Sedapap®
  • Tapanol®
  • Tylenol® with Codeine
  • Tylox®
  • Ultracet®
  • Vicodin®
  • Zydone®
  • *And generic medicines