Do not take more Fioricet than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).
You might be able to take other pain medications, like ibuprofen (Advil, Motrin) or naproxen (Aleve), with Fioricet if you need more relief for your headache. These medications work differently to ease pain and they can help lower the amount of Fioricet you need to relieve your symptoms. Taking less Fioricet means you’re not as likely to experience the dangers or side effects of taking this medication.
But don’t take other medications containing acetaminophen (Tylenol). Fioricet already contains acetaminophen, and you might accidentally take too much acetaminophen if you take these other medications and Fioricet together. This can lead to serious liver damage.
Before using other pain medications with Fioricet, speak with your healthcare provider to make sure it’s safe for you to do so. Other pain medications still carry risks that shouldn’t be ignored (e.g., heart risks, kidney problems).
In rare cases, acetaminophen may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
You should not use Fioricet if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
Do not use Fioricet if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.